Gene therapy cures type 1 diabetes in dogs

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Ramdev Baba’s claims to cure sugar related ailments notwithstanding,research carried out by Fatima Bosch, from Madrid based Universitat Autonoma deBarcelona (UAB), who led the study and obtained excellent results for the first time,showed that diabetes can be cured.

The reserachers claimed that after their discovered gene therapy,”the dogs recovered their health and no longer showed symptoms of the disease.”

Even Baba had said that by controlling diets and yoga,the type 1 diabetes can be over come.But Bosch is quoted by an ANI report saying,”This study is the first to demonstrate a long-term cure for diabetes in a large animal model using gene therapy.”

The same report said:

“Type 1 diabetes, also called juvenile diabetes or insulin-dependent diabetes, is a disorder of the body’s immune system.

The finding showed that after this treatment, the dogs recovered their health and no longer showed symptoms of the disease. In some cases, monitoring for over four years also bore out the same results, the journal Diabetes reports.

The therapy is minimally invasive and consists of a single session of various injections in the animal’s rear legs using simple needles that are commonly used in cosmetic treatments, according to an UAB statement.

These injections introduce gene therapy vectors, with a dual objective: to express the insulin gene, on the one hand, and that of glucokinase, on the other.
Glucokinase is an enzyme that regulates the uptake of glucose from the blood.

When both genes act simultaneously they function as a “glucose sensor”, which automatically regulates the uptake of glucose from the blood, thus reducing diabetic hyperglycemia (the excess of blood sugar associated with the disease).”

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